Our Expertise
Corporate Strategy
Planning for organizational growth and leadership
Strategy is about making choices—choices that allow organizations to strengthen their competitive position, create value for their stakeholders and align action with vision. Making the right choices requires clarity—clarity potential investors and partners seek before committing capital and resources; clarity clients and customers need to recognize and reward the value an organization creates; clarity an organization’s leaders need to sustain focus in the face of change; and clarity of mission essential to generating desired health, social and economic returns.
Shift Health helps leaders achieve clarity. We embark on systematic and engaging planning efforts that integrate the scientific, competitive and market evidence to make confident choices. We embrace a philosophy of co-creation with our clients to inspire a sense of ownership and readiness to act. And we prepare organizations to deliver on their strategies through a rational approach to implementation planning, setting clear roles, responsibilities and outcomes to ensure effective, measurable and accountable progress.
Strategic Planning – Business Planning – Implementation Planning
Shift Health is seeking an Engagement Leader with a science mindset in Toronto
Shift Health is seeking an Engagement Leader to join our dynamic team on a full-time, permanent basis. Application Deadline: November 27, 2024.
Shift Health is seeking a Senior Consultant with a science mindset in Toronto
Shift Health is seeking a Consultant to join our dynamic team on a full-time, permanent basis. Application Deadline: November 27, 2024.
Shift Health is seeking a Consultant with a science mindset
Shift Health is seeking a Consultant to join our dynamic team on a full-time, permanent basis. Application Deadline: November 27, 2024.
Shift Health Celebrates Another Year as one of HRD Canada’s Best Places to Work
Winners of this award prioritize employee needs, equip employees with tools and resources for success and foster a positive culture of shared purpose.
Save our Sight (SOS): a collective call-to-action for enhanced retinal care across health systems in high income countries
This peer-reviewed paper presents solutions to alleviate health system capacity constraints for retinal care.
Expert Consensus Paper on the Future Management of Retinal Disease Published in Eye
This peer-reviewed paper presents solutions to alleviate health system capacity constraints for retinal care.
Research Strategy
Research leadership in the context of scientific and technological change
Cutting-edge research strategies need to motivate investigators, attract partners and investment, inspire the public and remain ahead of the scientific curve. To serve these objectives, a research strategy must project substance: rooted in thoughtful perspectives on the direction of scientific knowledge and technology; informed by an honest appraisal of a research organization’s differentiating and competitive strengths; and positioned to address the priorities of patients, health systems and society.
Shift Health works with research funders, universities, academic health centres, research institutes and the private sector to develop substantive research strategies that position our clients at the scientific frontiers. Combined with deep business acumen, our backgrounds in health research allow us to speak the language of researchers in order to build trust and confidence, decipher scientific trends important to an organization’s future, and identify opportunities to unleash discovery and help organizations lead the way.
Disease Area Strategy – Innovation Strategy – Commercialization Strategy
Developing the Strategic Plan for CIHR’s Institute of Infection and Immunity
CIHR’s Institute of Infection & Immunity (III) engaged Shift Health to support the development of a 5-year strategic plan that reflected the research interests and strengths of Canada’s infection and immunity research community and the implications of the COVID-19 pandemic.
Putting Health Research on the Map in a Resource-based Economy
The Saudi Government aimed to create a national health research agency to strengthen the research and innovation ecosystem, support a learning healthcare system and diversify the Kingdom’s knowledge economy.
Uniting a Country Around a Single Vision for Cancer Research
Cancer research stakeholders across Canada recognized the need for a unifying vision that would inspire collective action and prepare Canada for leadership in a rapidly evolving cancer research landscape.
Positioning a Global Pharmaceutical Company’s HIV Portfolio to Capture Emerging Opportunities
Shift Health was engaged to support a top-5 global pharmaceutical company in defining its role and priorities in the evolving HIV disease management landscape.
Strengthening Clinical Research at a Community Hospital
Shift Health and University Health Network (UHN) were engaged by Halton Healthcare to assess the current state of research across a multisite hospital system and define the future direction of its clinical research program.
Advancing a Collaborative Vision and Strategy for the Global HIV Vaccine Enterprise
The International AIDS Society (IAS) required support to develop a 5-year strategy for the Global HIV Vaccine Enterprise (the Enterprise)—a long-time convenor and facilitator for the HIV vaccine R&D field.
Product Strategy
Positioning development programs for commercial success
Maximizing the value of a portfolio or an asset requires key elements to be in perfect alignment: alignment among scientific and commercial variables to ensure that development programs are addressing the right populations and markets; alignment with the payer and health system expectations that dictate whether the value of innovations will be recognized; and alignment across the cross-functional teams whose collective expertise is required to execute on development and commercialization plans.
Shift Health helps leaders—from multinational companies and smaller enterprises alike—achieve the alignment for successful product development. We efficiently collect the intelligence to understand a disease area and identify priority patient segments; we engage directly with payers, providers and patients to value-test hypothetical product profiles and expose nuances that differentiate development programs; and we work with internal teams to co-create market access strategies that position companies to mitigate risk and reach the market as quickly as possible.
R&D Strategy – Commercialization Plan – Market Access
Positioning a COVID-19 Vaccine Candidate in a Dynamic And Competitive Landscape
A top-5 pharmaceutical company sought to understand differentiating features of competitor COVID-19 vaccine programs and forecast regional market scenarios and commercial implications.
Uncovering Lifecycle Management Options to Maximize the Value of a Novel Antiviral Beyond Treatment of COVID-19
A global pharmaceutical giant engaged Shift Health to explore additional RNA virus indications to inform lifecycle management for a promising antiviral in clinical development for COVID-19.
Developing a Therapeutic Vaccine of Greatest Value to Patients and Systems
A top-5 pharmaceutical company sought the perspectives of payers in the US and major EU markets to ensure that the value of an innovative vaccine would ultimately be recognized by health systems.
Accelerating R&D Efforts Through Patient Data Repository Partnerships
A multinational pharmaceutical company sought support in developing a strategy to partner with public/academic cancer patient data repositories to advance its own R&D programs.
Assessing a Therapy’s Potential Use and Adoption in Treatment Resistant Depression
To support a mid-stage clinical development program, a top-5 pharmaceutical company engaged Shift Health to obtain an understanding of physicians’ decision-making process with alternative therapies.
Advancing a Pharmaceutical-Grade Cannabis Portfolio Positioned to Address Health Needs
A player in the medical cannabis space required support to uncover and catalogue scientific evidence that established the link between specific cannabis-based metabolites and their therapeutic benefit.
Opportunity Assessment
Life sciences investment analysis
Evaluating the attractiveness of investment opportunities in the life sciences—whether individual assets, multifaceted portfolios or entire companies—is a complex exercise that requires both instinct and precision: the instinct to recognize the scientific and clinical promise of an asset, envision the path to market, and anticipate the perceptions of customers, payers and end-users; the investment-grade precision to forecast commercial potential and support a clear decision.
Integrating depth in business, science and healthcare, Shift Health brings discerning instinct and data-driven precision to opportunity assessment. Our track record evaluating a spectrum of investment scenarios, therapy areas and asset classes across diverse and increasingly convergent sectors allows us to apply proven analytical frameworks that separate signals from the noise. We are adept at translating relevant evidence into dynamic and multivariate financial models that support sound valuations our clients can trust.
Opportunity Identification — Opportunity Evaluation — Financial Modeling
Uncovering Risks and Forecasting Performance of a Royalty Portfolio to Guide Investment Decisions
A large institutional investment firm engaged Shift Health to evaluate the products in a portfolio of pharma royalties it had an opportunity to acquire.
Balancing an Innovative Biotechnology Company’s Oncology Portfolio
A US-based biotech company required support to identify, evaluate and prioritize novel immunotherapies and targeted oncology drug candidates to supplement its clinical pipeline.
Assessing the Market for Novel Image Guidance Systems for Minimally Invasive Cardiac Interventions
An Asian specialty healthcare company needed to assess the US market for novel image guidance medical device systems for minimally invasive cardiac interventions.
Bolstering a Leading Biopharmaceutical Company’s Oncology Franchise
A top-5 global biopharmaceutical company wanted to identify promising oncology drug candidates that it could in-license or acquire to bolster its oncology franchise revenues over the near term.
Building Investor Confidence in a Vaccine Investment Decision
Shift Health was engaged by a leading US investment firm to evaluate an asset and project sales in order to inform their decision to invest in an established biotechnology company expanding into new markets.
Policy Strategy
Creating a policy environment that supports innovation
A favourable policy environment is critical to the success of health innovation—setting the context in which a research-intensive organization will flourish or fail, make the decision to invest, or expect the value of its innovations to be recognized and rewarded. Sound policy strategy must be rooted in objectivity: objectivity that rises above narrow commercial interests; objectivity that avoids spin and considers evidence contrary to desired messaging; and objectivity that helps policymakers make the best decisions on behalf of their public constituencies.
Shift Health supports policy teams in creating evidence-based strategies and communication materials to navigate, inform and influence the complex web of policy and related stakeholders. Through the pursuit and presentation of impartial evidence, we help our clients develop ironclad advocacy positions that serve long-term interests. We are forthright when the data do not support a preferred position; and we bring a discerning eye to create responsible policy strategies that build credibility, enable policy partnership, and serve both societal and corporate interests.
Strategic Planning – Business Planning – Implementation Planning
Inspiring Urgency Needed to Tackle Alzheimer’s Disease
A top-5 pharmaceutical company needed to prepare decision-makers for the patient and health system impact of disease-modifying therapies and diagnostic biomarkers for Alzheimer’s disease.
Preparing Policymakers for the Next Generation of Personalized Medicine
A large biotech firm needed support in developing an evidence-based policy narrative in preparation for the launch of a CAR T-cell therapy for a rare form of cancer.
Creating a Global Policy Strategy to Support the Launch of an Innovative Influenza Antiviral for a Top-5 Pharma Company
The global headquarters of a top-5 pharmaceutical company needed to develop a global policy strategy to support the launch of a new treatment for influenza.
Creating the Personalized Healthcare System of the Future
A global biopharmaceutical company recognized the need to work in partnership with healthcare systems in order to realize the vital, long-term potential of a personalized approach to healthcare.
Exploring Patient and Caregiver Perspectives to Improve the Haemophilia Treatment Environment
A multinational pharmaceutical company sought support to engage with haemophilia A individuals and caregivers to gather firsthand perspectives on the impact of current and value of future therapies.
Partnership Strategy
Development and management of R&D alliances
Health research and innovation are high-risk and resource-intensive, and multidisciplinary, multisector partnerships are increasingly pivotal to sharing risk, sustaining efforts, diversifying opportunities and achieving impact. Developing a successful alliance requires creativity and empathy: the creativity to build collaborative models that reflect the unique needs of the partners and embed the resilience to thrive in a rapidly changing research landscape; the empathy to engage with diverse personalities, find common ground and coalesce parties around a shared mission.
Shift Health advises some of the world’s most complex and ambitious R&D alliances and brings a deep understanding of the intricacies involved in brokering, mobilizing and governing partnerships that span sectors, disciplines and geographies. Our work across the health innovation ecosystem affords us an appreciation of the perspectives of groups with divergent agendas; an ability to align common interests and build consensus where objectives compete; and the experience to create durable decision-making structures that foster clarity, fairness and accountability.
Partnership Evaluation – Partnership Governance – Alliance Management
Advancing a Bold Model to Combat Pandemic and Biological Threats
Recognizing that our traditional models to pandemic preparedness have failed to imagine the risk and broad societal impact of biological threats, McMaster University sought support to establish a new way forward.
Building the Case for Biopharma Industry Investment in Strep A Vaccine Development
A global health consortium required support in attracting greater industry investment into the traditionally underfunded area of Strep A vaccine development.
Leveraging External Partnerships to Maximize the Value of a Top-5 Pharma’s Portfolio
In the face of constrained R&D budgets, a top-5 pharmaceutical company needed support to develop a transformative, corporate-wide strategy to assess and secure external funding.
De-Risking Vaccine Development Through a Translational Research Public-Private Partnership
Facing the need to de-risk the development of new vaccines, a top-10 biopharma company required help articulating the strategic vision and business case for a translational research public-private partnership.
Ensuring the World is Ready for the World’s First HIV Vaccine
The Pox-Protein Public-Private Partnership (P5) is tackling an enduring and daunting challenge: developing the world’s first HIV vaccine and ensuring it achieves maximum public health impact.
Accelerating the Development of MERS-CoV Technologies
The International Vaccine Institute in South Korea and the Saudi Ministry of Health required strategic and facilitation support to advance a collaborative approach to MERS-CoV vaccine development.
Program Evaluation
Performance and impact assessment
Objective, independent evaluation is critical to understanding, verifying and communicating an organization’s achievements, exposing new opportunities to create value, and defending the case for continued support and investment. To be credible, evaluations must demonstrate rigour: they must be comprehensive, addressing impact against all relevant dimensions of an organization’s strategy; meticulous, capturing and/or generating the necessary data to address the full scope of the evaluation; and accurate, providing full confidence in indisputable outputs.
Shift Health takes a scientifically rigorous approach to program evaluation. We use analytical frameworks that eliminate noise and discriminate what’s essential to understanding performance; we deploy multimodal approaches to collect meaningful data; we apply scorecards to support unbiased analysis; and we communicate findings with sensitivity to an organization’s context and target audience. While program evaluation is inherently retrospective, we view it as a step forward, exposing new opportunities that will position organizations for future impact.
Tailored Scorecards – Performance Assessment – Future Directions
Evaluating SCPOR’s Impact on Patient-Oriented Research
The Saskatchewan Centre for Patient-Oriented Research (SCPOR) needed a third-party evaluation to understand its impact to date and optimize its strategy.
Demonstrating the Impact of OSSU’s Model for Fortifying Patient-Oriented Research
Ontario SPOR SUPPORT Unit (OSSU) needed to develop and pilot an evaluation tool to assess the impact of its multi-sectoral approach to patient-oriented research at the midpoint of its funding cycle.
Evaluating the Current State of Cancer Clinical Trials in Canada
The Canadian Cancer Research Alliance (CCRA) wanted to better understand the cancer clinical trial landscape in Canada, and in particular, the contribution of its initiatives to promoting access to trials.
Assessing Operational Efficiency and Strategic Alignment of an Infectious Disease Research Institute
Shift Health was engaged to conduct an independent operational review of an infectious disease research institute funded and operated by the US and Thai governments.
Evaluating Impact and Cost-Efficiency of Knowledge Transfer Activities in the Agri-Food Sector
To inform future knowledge transfer efforts, the Ontario Ministry of Agriculture, Food and Rural Affairs (OMAFRA) needed to assess activities delivered under the Growing Forward 2 program.
Proposals and Pitches
Investment attraction for strategic initiatives
Success in attracting buy-in and raising capital for research and innovation initiatives depends in part on how well the opportunity is positioned for and communicated to target audiences. Potential funders and investors seek proposals and pitches that convey credibility: the credibility that underpins anticipated commercial, social and health returns; the credibility that provides confidence in the scientific and operational feasibility of the strategy; and the credibility of the proponents and partners whose demonstrable leadership in relevant domains will assure success.
Having helped to raise well over a billion dollars for health research initiatives, Shift Health knows what it takes to produce a proposal that’s compelling, differentiating and indisputably credible. We take advantage of our scientific backgrounds to understand the technical aspects of proposals and convey scientific ideas strategically; we build on our track record working with funders and investors directly to align agendas and craft powerful messaging; and we apply our creativity to produce eloquent, visually impactful materials that effectively communicate complex concepts.
Grant Applications – Business Cases – Investor Material
Advancing a Bold Model to Combat Pandemic and Biological Threats
Recognizing that our traditional models to pandemic preparedness have failed to imagine the risk and broad societal impact of biological threats, McMaster University sought support to establish a new way forward.
Attracting $100M in Government Support for the Ontario Brain Institute
The Ontario Brain Institute (OBI) needed to define its strategic direction and articulate its value to policymakers to ensure continued government support for brain research.
Securing $83M in Government Funding for a Water Research Program
The University of Saskatchewan needed a compelling proposal to secure investment from the Canada First Research Excellence Fund (CFREF) for a water security research program.
Unlocking $120M in Investments for Brain Health Innovation
Shift Health was engaged by Baycrest Health Sciences to develop a business plan and operating model for the multinational, multi-partner Centre for Aging and Brain Health Innovation (CABHI).
Securing $15M for a Microbiome Research and Drug Discovery Program
McMaster University sought to secure a $15M investment to support the creation of a research program focused on studying host microbe interactions and the development of new antimicrobial agents.
Supporting Investor Engagement to Raise Funding for a New Research Institute
Shift Health was engaged by Ryerson University to develop a briefing note to engage investors for an institute focused on advancing the R&D of biomedical engineering technologies.